Effects of a Fasting-Mimicking Diet on Long-Term Prognosis in Colorectal Cancer After Radical Resection: Trial Protocol

تأثيرات حمية تحاكي الصيام على التنبؤ طويل الأمد لدى مرضى سرطان القولون والمستقيم بعد الاستئصال الجذري: بروتوكول تجربة متعددة المراكز

Journal: BMJ open

University: PubMed

Study Type: clinical trial

Evidence Level: low

Participants: 602

Published:

⚠️ Warning: This is a preliminary study (animal/cell) and has not been proven in humans.

30-Second Summary

This is a multicenter randomized controlled trial protocol in China testing a fasting-mimicking diet (FMD) in 602 stage III colorectal cancer patients after radical resection. Participants undergo a 4-month dietary intervention with 3 years follow-up; the primary outcome is 3-year disease-free survival. The study is ongoing with expected completion in December 2027.

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    DOI: 10.1136/bmjopen-2026-121738

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